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with ACI™

The Most Intelligent Flash Chromatography System in the World 

Isolera™ Spektra is a high performance ACI™ Accelerated Chromatographic Isolation system. Available as Isolera Spektra One, Four and LS, with time, efficiency and cost saving purification run features that are normally only found on the world’s most expensive high-end chromatography systems.


Bringing Mass Detection to Flash Chromatography 

The Isolera™ Dalton system consists of Isolera™ Dalton Mass Detector, Isolera™ Dalton Nanolink and Isolera™ Spektra and embraces ACI™ for efficient and automated purification. Isolera Dalton directs flash fractionation by molecular mass, and in real time.


TriVersa NanoMate® 

The TriVersa NanoMate is the latest in chip-based electrospray ionization technology from Advion.
It combines the strengths of liquid chromatography, mass spectrometry, chip-based infusion, fraction collection, and direct surface analysis into one integrated system. It allows analysts to obtain more information from complex samples than with LC/MS alone.

The Industry Standard Original Process Scale Purification 

When considering larger, production scale equipment, robustness and safety are key factors for any device. The Flash 75/150/400 systems need minimal maintenance and their design has proven to be extremely reliable over many years. These systems allowing operators to save hours or even days of separation time.

Scalable results

Technologies such as crystallization and adsorption can be difficult and time consuming to scale up. With Biotage’s extensive cartridge range, reliable results are verifiable and easy to achieve with any separation.

Purify up to 400 grams of compound at 1L/min up to 75% faster than with traditional glass columns. Biotage® Flash 75/150 is a simple and reliable system that contains everything you need for separation scale up.

Often a separation is done with a Biotage® SNAP 10 g column to purify small quantities and those conditions can be used again on larger columns all the way up to 40 kg Flash 400L size, a 4000x increase in scale.